Product Sheet: Profiling chromatin accessibility at single cell resolutionġ0x Genomics' new Chromium Nuclei Isolation Kit removes the complexities of nuclei isolation with an easy-to-use solution specifically designed for use with 10x Genomics single cell assays for gene expression and chromatin accessibility. Compatibility with the new Chromium Nuclei Isolation Kit, an easy-to-use kit optimised for 10x Genomics single cell assays, which streamlines sample prep for a wide range of frozen sample types.Deeper characterisation of complex samples, including enhanced ability to detect rare peaks.Increased usable reads, thereby improving signal-to-noise ratio.50% higher sensitivity, depending on sample type.Building upon v1.1 chemistry, the v2 assay provides increased sensitivity and improved signal-to-noise ratio, enhancing your ability to detect rare peaks. The first commercial single cell multiomics product for simultaneous profiling of gene expression and chromatin landscape at single cell resolution.Ĭhromium Single Cell ATAC v2 is now shipping!Ĭhromium Single Cell Assay for Transposase Accessible Chromatin (ATAC) is a powerful method to understand gene regulation and characterise cell types and states, all at the single cell level. Top of page Single Cell Multiome ATAC + Gene Expression Leverage dual index libraries for superior sequencing data quality.
Utilise product partners for Feature Barcode technology (oligo-conjugated antibodies, oligo-conjugated MHCs) to easily perform multiomic profiling.Combine with Targeted Gene Expression Panels to focus on the genes that matter most and accelerate your studies into actionable insights.Obtain paired, full-length receptor sequences from T cells and/or B cells with complete isotype resolution, providing functional data for antibody/TCR discovery.Simultaneously profile immune repertoire (BCR/TCR) and gene expression from the same cell to enable correlation of clonotype with the corresponding cell subtype.Profile thousands of genes at the single cell level by barcoding mRNA at the 5' end, for unbiased characterisation of cell types and cell states Level up your insights by combining single cell gene expression data with spatial gene expression.Singlets are single cells or nuclei captured after multiplet removal.Combine with 3' CellPlex to multiplex up to 12 samples and recover up to 17,500 singlets* per channel, enabling larger-scale single cell studies.Leverage dual index libraries for reliable sequencing data quality.Simultaneously assess CRISPR perturbation phenotypes and gene expression from the same cell to accelerate your functional genomics studies.Use with Targeted Gene Expression panels to focus on the genes and biomarkers most relevant to your research.Combine gene expression analysis with detection of hundreds of cell surface proteins at high resolution for ultra-high parameter multiomic cytometry.Profile thousands of genes at the single cell level for unbiased characterization of cell types and cell states Start from fresh or PFA-fixed samples, or even FFPE tissues from clinical trials or other translational studies.Batch and multiplex samples to improve efficiency, minimize handling, and reduce per-sample costs by up to 75%.Run assays on your schedule and simplify handling with the ability to store and transport samples without losing data quality.This powerful probe-based assay boosts your discovery power, enabling you to: Single cell technology is now better equipped to help unravel biological complexity. The latest addition to the Chromium platform, Single Cell Gene Expression Flex, brings our most sensitive single cell assay to your bench, with flexible options for everything from pilot experiments to million-cell studies. Gene Expression (for FFPE & Fresh Frozen Tissue)Ĭhromium Single Cell Gene Expression Flex.Immune Profiling (with Antigen Specificity & Cell Surface Protein).Gene Expression (with Cell Surface Protein).Chromium Single Cell Gene Expression Flex.
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